I. An Investigation of the Utility of the Claisen Rearrangement in Angular Methylation as Illustrated by the Synthesis of 1-Valeranone. II. The Total Synthesis of the Pentacyclic Triterpene dl-Germanicol

Author: Dawson, Daniel Joseph

Year: 1971

Degree: Dissertation (Ph.D.)

Advisor: Ireland, Robert E.

Committee Member: Unknown, Unknown

Option: Chemistry

DOI: 10.7907/A7NX-WW98

Abstract

I. A new method of angular methylation was developed in a synthesis of 1-valeranone. This Claisen rearrangement-- decarbonylation procedure was further investigated on the substrate cholest-4-en-3β-o1.

II. The synthesis of the pentacyclic triterpene dl-germanicol is described.

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