The Total Synthesis of the Enantiomer of Lasalocid A

Author: Fitzsimmons, Brian Joseph

Year: 1984

Degree: Dissertation (Ph.D.)

Advisor: Grubbs, Robert H.

Committee Members: Grubbs, Robert H.; Ireland, Robert E.; Goddard, William A., III; Anson, Fred C.

Option: Chemistry

DOI: 10.7907/w5gn-5650

Abstract

A convergent total synthesis of the enantiomer of the naturally occurring polyether antibiotic Lasalocid A (X-537A) and preliminary results of the biological testing of this compound are reported.

Files

• Fitzsimmons_BJ_1984.pdf (application/pdf)