Chemical Tools for the Control of Biological Systems

Author: Jarman, John Bryce

Year: 2019

Degree: Dissertation (Ph.D.)

Advisor: Dougherty, Dennis A.

Committee Members: Dervan, Peter B.; Shan, Shu-ou; Grubbs, Robert H.; Dougherty, Dennis A.

Option: Chemistry

DOI: 10.7907/MV3V-2R09

Abstract

Described within is an exploration of noncanonical amino acids and photochemistry in the context of chemical biology. The thesis first covers attempts to expand the use of chemically acylated tRNA into new systems, before describing explorations into singlet oxygen as a powerful photochemical tool.

Files

• JBJ_Thesis_Final.pdf (application/pdf)