A Study of the Interaction between Calf Thymus Desoxyribonucleic Acid and Tetramethylammonium Ions

Author: Johnson, Arthur Edward

Year: 1964

Degree: Bachelor's thesis

Advisor: Davidson, Norman R.

Committee Member: Unknown, Unknown

Option: Chemistry

DOI: 10.7907/7q12-zv85

Abstract

Heat denaturation studies of desoxyribonucleic acid in sodium chloride and tetramethylammonium chloride solutions of low ionic strength have shown that DNA melts at a lower temperature in the TMACl solutions.

Electrophoresis experiments with DNA in a low ionic strength TMACl medium have disclosed that DNA has only a slightly higher mobility in 0.01 F TMACl than in 0.01 F NaCl.

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