The Cyclization of 5-isopropyl-3-methyl-2(3-n-pentenyl)-2-cyclohexene-1-one

Author: Miller, Robert John

Year: 1967

Degree: Bachelor's thesis

Advisor: Brown, Morris

Committee Member: Unknown, Unknown

Option: Chemistry

DOI: 10.7907/s1m8-w430

Abstract

Several possible approaches toward effecting the cyclization of 5-isopropyl-3-methyl-2(3-n-pentenyl)-2-cyclohexen-1-one (I) to the decanone (II) are studied. Acid-catalysts, such as polyphosphoric acid and boron trifluoride, are found to be ineffective acting directly on the cyclohexenone. The cyanohydrin of (I) was found to be the unpreferred product in the cyanide reaction, thus eliminating that activated form as a means to effecting the cyclization.

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