I. A Theoretical Study of the Representation of Genomic Sequences in Partial Digest Libraries. II. Studies of the Bacteriophage T4 Proximal Half Tail Fiber

Author: Seed, Brian

Year: 1981

Degree: Dissertation (Ph.D.)

Advisor: Unknown, Unknown

Committee Member: Unknown, Unknown

Option: Biochemistry

DOI: 10.7907/q0qd-9933

Abstract

Part I of this thesis is a theoretical investigation of the fraction of a (suitably idealized) genomic DNA which can be found among restriction enzyme partial digest fragments having lengths between Land L+r basepairs long.

Part II of this thesis summarizes some experimental investigations of the structure and evolution of the bacteriophage T4 proximal half tail fiber, its interactions with the distal half-fiber, and the variety of phenotypes exhibited by temperature-sensitive mutations in its structural gene.

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