I. The Synthesis of Conformationally Stable Carbohydrates. II. Studies on Synthetic Sesquiterpenes Related to Eremophilone

Author: Piszkiewicz, Leonard William

Year: 1967

Degree: Dissertation (Ph.D.)

Advisors: Niemann, Carl G.; Brown, Morris

Committee Member: Unknown, Unknown

Option: Chemistry

DOI: 10.7907/QR4E-KN36

Abstract

I. The synthesis of conformationally stable carbohydrates by use of the dialdehyde cyclization method of Baer and Fischer has been investigated. The synthesis of two new 3-C-alkyl-3-aminoaldohexose derivatives was achieved and the full structure elucidation of one of these compounds, methyl 3-isopropyl-3-amino-3-deoxy-[alpha]-D-gulopyranoside hydrochloride, has been accomplished.

II. A study of the stereoselective synthesis of compounds related to eremophilone by use of the Michael reaction has been performed and the synthesis of compounds stereochemically related to eremophilone has been accomplished.

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