Experiments Directed Towards the Total Synthesis of Chlorothricolide

Author: Heckendorn, Debra Kay

Year: 1983

Degree: Master's thesis

Advisor: Ireland, Robert E.

Committee Member: Unknown, Unknown

Option: Chemistry

DOI: 10.7907/q3v3-m204

Abstract

The attempted synthesis of a differentially protected "top half", i, of chlorothricolide is described. The key step necessary for this synthesis was the spirocyclization of the anhydride ii, to prepare the protected tetronic acid iii.

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