Charge-Transfer Association in Enzyme Inhibition

Author: Roth, Dana Lincoln

Year: 1965

Degree: Master's thesis

Advisor: Niemann, Carl G.

Committee Member: Unknown, Unknown

Option: Chemistry

DOI: 10.7907/DPPB-6X75

Abstract

Attempts to determine if charge-transfer bonding forces are involved in enzyme inhibition by gas chromatographic and spectral methods were, in general, unsuccessful.

Direct spectral evidence of formation of the β-naphthoquino-linium cation in the presence of the enzyme, α-chymotrypsin, has been shown.

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