Arnold, Frances Hamilton

Advisor — 55 thesises

Johnston, Kadina Elizabeth — Acquiring Enzyme Sequence-Fitness Data at Scale Toward Predictive Methods for Enzyme Engineering (2024, Dissertation (Ph.D.))
Yang, Jason — Artificial Intelligence Methods for Enzyme Engineering (2026, Dissertation (Ph.D.))
Zhou, Andrew Z. — Biocatalytic Lactone Carbene C–H, B–H, and N–H Insertion Reactions Enabled by Directed Evolution (2021, Senior thesis (Major))
Carbone, Martina Nini — Characterization of the Functional Diversity and Evolvability of Chimeric Enzymes Assembled by Structure-Guided SCHEMA Recombination (2010, Dissertation (Ph.D.))
Voigt, Christopher Ashby — Computationally Optimizing the Directed Evolution of Proteins (2003, Dissertation (Ph.D.))
Long, Yueming — Data Foundations for Functional Prediction in Enzyme Engineering (2026, Dissertation (Ph.D.))
Wu, Zachary — Data-Driven Protein Engineering (2021, Dissertation (Ph.D.))
Endelman, Jeffrey B. — Design and Analysis of Combinatorial Protein Libraries Created by Site-Directed Recombination (2005, Dissertation (Ph.D.))
Tobias, Alexander Vincent — Directed Evolution of Biosynthetic Pathways to Carotenoids with Unnatural Carbon Backbones (2006, Dissertation (Ph.D.))
Chen, Mike Ming Yu — Directed Evolution of Cytochrome P450 for Small Alkane Hydroxylation (2011, Dissertation (Ph.D.))
Kalbarczyk, Karolina Zbigniew — Directed Evolution of Terpene Synthases for Non-Natural Substrates (2013, Senior thesis (Major))
Collins, Cynthia Hollie — Directed Evolution of the Transcriptional Activator LuxR (2006, Dissertation (Ph.D.))
Farwell, Christopher C. — Engineering and Characterization of Cytochrome P450 Enzymes for Nitrogen-Atom Transfer Reactions (2015, Dissertation (Ph.D.))
Meinhold, Peter — Engineering Cytochrome P450 BM-3 for Selective Hydroxylation of Alkanes (2005, Dissertation (Ph.D.))
Sarai, Nicholas Singh — Engineering Cytochrome P450BM3 for Oxidation and Silicon–Carbon Bond Cleavage of Volatile Methylsiloxanes (2023, Dissertation (Ph.D.))
Joern, John Michael — Engineering Dioxygenases by Laboratory Evolution: A Comparison of Evolutionary Search Strategies (2003, Dissertation (Ph.D.))
Trudeau, Devin Lee — Engineering Enzyme Systems by Recombination (2014, Dissertation (Ph.D.))
Sun, Lianhong — Engineering Galactose Oxidase to Increase Expression Level in E. coli, Enhance Thermostability and Introduce Novel Activities (2003, Dissertation (Ph.D.))
Gao, Shilong — Engineering Heme Proteins for C(sp³)–H Primary Amination (2024, Dissertation (Ph.D.))
Zhang, Ruijie — Engineering Heme Proteins for Olefin and Carbon−Hydrogen Bond Functionalization Reactions (2019, Dissertation (Ph.D.))
Bedbrook, Claire Nicole — Engineering Novel Rhodopsins for Neuroscience (2018, Dissertation (Ph.D.))
Brenner, Sarah Katherine — Engineering Synthetic Biofilm-Forming Microbial Consortia (2009, Dissertation (Ph.D.))
Watkins-Dulaney, Ella Jenná — Engineering the Tryptophan Synthase β-Subunit for Synthesis of Noncanonical Amino Acids (2022, Dissertation (Ph.D.))
Wu, Indira — Engineering Thermostable Fungal Cellobiohydrolases (2013, Dissertation (Ph.D.))
Cahn, Jackson Kenai Blender — Engineering, Predicting, and Understanding Nicotinamide Cofactor Specificity (2016, Dissertation (Ph.D.))
Zhao, Huimin — Enzyme Design by Directed Evolution (1998, Dissertation (Ph.D.))
Li, Francesca-Zhoufan — Evaluation of the Generalizability of Machine Learning-Assisted Protein Engineering Methods (2025, Dissertation (Ph.D.))
Lewis, Russell DeRieux — Evolution and Characterization of Carbene Transferases for Cyclopropanation and Carbon–Silicon Bond Formation (2019, Dissertation (Ph.D.))
Lal, Ravi Goel — Expanding Enzyme Function Through Data-Guided Evolution (2026, Dissertation (Ph.D.))
Chen, Kai — Expanding the Catalytic Repertoire of Hemeproteins as Carbene Transferases to Access Diverse Molecular Structures (2020, Dissertation (Ph.D.))
Qin, Ziyang — Expanding the Chemical Space of Nitrene Transferases: Biocatalytic Construction of C–N Bonds (2026, Dissertation (Ph.D.))
Knight, Anders Matthew — Expanding the Scope of Metalloprotein Families and Substrate Classes in New-to-Nature Reactions (2021, Dissertation (Ph.D.))
Claeys, Ivan Lode André Maria — Experimental and Numerical Study of Molecular Rotational Diffusion in Gel-Like Media (1988, Master's thesis)
Meyer, Michelle Margaret — Exploring Protein Sequence Space Using Computationally Directed Recombination (2006, Dissertation (Ph.D.))
Bloom, Jesse D. — Hidden Dimensions in Protein Evolution: Stability, Mutational Robustness, and Evolvability (2007, Dissertation (Ph.D.))
Cirino, Patrick Carmen — Laboratory Evolution of Cytochrome P450 Peroxygenase Activity (2004, Dissertation (Ph.D.))
Fu, Anne Yen-Chen — Microfabricated Fluorescence-Activated Cell Sorters (µFACS) for Screening Bacterial Cells (2002, Dissertation (Ph.D.))
Thorsen, Todd Addison — Microfluidic Technologies for High-Throughput Screening Applications (2003, Dissertation (Ph.D.))
Drummond, David Allan — Misfolding Dominates Protein Evolution (2006, Dissertation (Ph.D.))
Johnson, Robert David — Multivalent Protein Binding to Metal-Complexing Materials: Applications to Synthetic Receptors and Affinity Chromatography (1995, Dissertation (Ph.D.))
Wackelin, Daniel Joseph — New to Nature C–C Bond Forming Cyclases: Pushing the Boundaries of Ring Forming Reactions (2024, Dissertation (Ph.D.))
Zhang, Juner — New-to-Nature Selective C-H Alkylation Using Engineered Carbene Transferases (2022, Dissertation (Ph.D.))
Smith, Matthew Alexander — Non-Contiguous Protein Recombination (2013, Dissertation (Ph.D.))
Goldberg, Nathaniel Wood — Non-Native Chemistry of Metalloenzymes (2022, Dissertation (Ph.D.))
Almhjell, Patrick James — Noncanonical Amino Acid Synthesis by Evolved Tryptophan Synthases (2023, Dissertation (Ph.D.))
Coelho, Pedro de Souza Leão — Olefin Cyclopropanation and Carbon-Hydrogen Amination via Carbene and Nitrene Transfers Catalyzed by Engineered Cytochrome P450 Enzymes (2013, Dissertation (Ph.D.))
Udit, Andrew K. — P450 BM3 Electrochemistry and Electrocatalysis (2005, Dissertation (Ph.D.))
Yang, Kevin Kaichuang — Probabilistic Protein Engineering (2019, Dissertation (Ph.D.))
Pack, Daniel W. — Protein Targeting to Metal-Chelating Lipid Monolayers: Toward New Materials Inspired by Nature (1997, Dissertation (Ph.D.))
Komor, Russell Scott — Recombinatorial and Predictive Methods to Increase Cellulase Thermostability and Structural Analysis of a Thermostable P450 (2012, Dissertation (Ph.D.))
Romero, Philip Anthony — Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering (2012, Dissertation (Ph.D.))
Wittmann, Bruce James — Strategies and Tools for Machine Learning-Assisted Protein Engineering (2022, Dissertation (Ph.D.))
Otey, Christopher Richard — Structural and Functional Exploration of an Artificial Family of Cytochromes P450 (2008, Dissertation (Ph.D.))
Shnek, Deborah Rebecca — Targeting of Proteins and Protein Analogs to Metal-Chelating Lipid Vesicles (1996, Dissertation (Ph.D.))
O'Meara, Ryen Logan — Towards the Enzymatic Mineralization of Siloxanes (2026, Dissertation (Ph.D.))