Arnold, Frances Hamilton

Committee Member — 105 thesises

• Nisthal, Alex — Accelerating the Interplay Between Theory and Experiment in Protein Design (2012, Dissertation (Ph.D.))
• Johnston, Kadina Elizabeth — Acquiring Enzyme Sequence-Fitness Data at Scale Toward Predictive Methods for Enzyme Engineering (2024, Dissertation (Ph.D.))
• Shah, Premal S. — Advances in Force Field Development and Sequence Optimization Methods for Computational Protein Design (2005, Dissertation (Ph.D.))
• McQueen, Anne T. — Ammonium Ion Effects on Hybridoma Cell Physiology (1989, Dissertation (Ph.D.))
• Moore, Matthew Michaels — Applications of Computational Protein Design to Red Fluorescent Proteins (2013, Dissertation (Ph.D.))
• Yang, Jason — Artificial Intelligence Methods for Enzyme Engineering (2026, Dissertation (Ph.D.))
• Link, Aaron James — Azide-Bearing Amino Acids in Protein Engineering and Proteomic Profiling (2006, Dissertation (Ph.D.))
• Szablowski, Jerzy Olgierd — Biological Activity of Pyrrole-Imidazole Polyamides in vivo (2015, Dissertation (Ph.D.))
• Babin, Brett Michael — Bioorthogonal Noncanonical Amino Acid Tagging for Selective Analysis of the Pseudomonas aeruginosa Proteome (2016, Dissertation (Ph.D.))
• Van Deventer, James A. — Biophysics and Protein Engineering with Noncanonical Amino Acids (2011, Dissertation (Ph.D.))
• Son, Soojin — Biosynthetic Approaches to Protein Engineering Using Fluorinated Amino Acids (2007, Dissertation (Ph.D.))
• Wang, Jingzhou — CDRxAb: Antibody Small-Molecule Conjugates with Computationally Designed Target-Binding Synergy (2021, Dissertation (Ph.D.))
• Carbone, Martina Nini — Characterization of the Functional Diversity and Evolvability of Chimeric Enzymes Assembled by Structure-Guided SCHEMA Recombination (2010, Dissertation (Ph.D.))
• Hart, Roger A. — Characterization of Vitreoscilla hemoglobin inclusion bodies produced in Escherichia coli (1991, Dissertation (Ph.D.))
• Michener, Joshua Kieran — Combining Rational and Evolutionary Approaches to Optimize Enzyme Activity in Saccharomyces cerevisiae (2012, Dissertation (Ph.D.))
• Wannier, Timothy Milton — Computationally Guided Monomerization of Red Fluorescent Proteins of the Class Anthozoa (2015, Dissertation (Ph.D.))
• Voigt, Christopher Ashby — Computationally Optimizing the Directed Evolution of Proteins (2003, Dissertation (Ph.D.))
• Lee, Toni Marie — Computationally-Guided Thermostabilization of the Primary Endoglucanase from Hypocrea jerorina for Cellulosic Biofuel Production (2014, Dissertation (Ph.D.))
• Liontas, Rachel — Controlling Deformability in Metallic Glass Nanopillars and Nanolattices (2017, Dissertation (Ph.D.))
• Watnick, Paula Ivonne — Cooperative Properties of Lipid Bilayers: Collective Director Fluctuations and the Effects of Hydrophobic Mismatch in Protein/Lipid Membrane Systems (1989, Dissertation (Ph.D.))
• Long, Yueming — Data Foundations for Functional Prediction in Enzyme Engineering (2026, Dissertation (Ph.D.))
• Wu, Zachary — Data-Driven Protein Engineering (2021, Dissertation (Ph.D.))
• Reardon, Kenneth Frederick — Deactivation and Regeneration Kinetics during Bioconversions by Immobilized Clostridium acetobutylicum (1988, Dissertation (Ph.D.))
• Endelman, Jeffrey B. — Design and Analysis of Combinatorial Protein Libraries Created by Site-Directed Recombination (2005, Dissertation (Ph.D.))
• Grant, Stanley Clement Baugh — Detection and partitioning of bacteriophage in fluid/solid systems: application to the ecology and mobility of viruses in the environment (1992, Dissertation (Ph.D.))
• Vizcarra, Christina Luisa — Development and Evaluation of Protein Design Methods for Functional Targets (2008, Dissertation (Ph.D.))
• Allen, Benjamin Daniel — Development and Validation of Optimization Methods for the Design of Protein Sequences and Combinatorial Libraries (2009, Dissertation (Ph.D.))
• Agbo, Peter Chukwudi Ifeanychukwu — Development of Metalloenzyme Dioxygen Reduction Cathodes (2015, Dissertation (Ph.D.))
• Tobias, Alexander Vincent — Directed Evolution of Biosynthetic Pathways to Carotenoids with Unnatural Carbon Backbones (2006, Dissertation (Ph.D.))
• Chen, Mike Ming Yu — Directed Evolution of Cytochrome P450 for Small Alkane Hydroxylation (2011, Dissertation (Ph.D.))
• Collins, Cynthia Hollie — Directed Evolution of the Transcriptional Activator LuxR (2006, Dissertation (Ph.D.))
• Huang, Shan — DNA-Guided Genome Manipulation in Escherichia coli (2023, Dissertation (Ph.D.))
• Romano, Christine Anne — DNA-Mediated Charge Transfer Between [4Fe-4S] Cluster Glycosylases (2011, Dissertation (Ph.D.))
• Galazzo, Jorge Luis — Effects of Cell Entrapment in Ca-Alginate on the Metabolism of Yeast Saccharomyces cerevisiae (1989, Dissertation (Ph.D.))
• Lee, Cin-Young — Efficient Automatic Engineering Design Synthesis Via Evolutionary Exploration (2002, Dissertation (Ph.D.))
• Totoiu, Christian Alexander — Electron Spin-Based Quantum Sensing in Biomolecular Systems (2026, Dissertation (Ph.D.))
• Farwell, Christopher C. — Engineering and Characterization of Cytochrome P450 Enzymes for Nitrogen-Atom Transfer Reactions (2015, Dissertation (Ph.D.))
• Meinhold, Peter — Engineering Cytochrome P450 BM-3 for Selective Hydroxylation of Alkanes (2005, Dissertation (Ph.D.))
• Sarai, Nicholas Singh — Engineering Cytochrome P450BM3 for Oxidation and Silicon–Carbon Bond Cleavage of Volatile Methylsiloxanes (2023, Dissertation (Ph.D.))
• Joern, John Michael — Engineering Dioxygenases by Laboratory Evolution: A Comparison of Evolutionary Search Strategies (2003, Dissertation (Ph.D.))
• Trudeau, Devin Lee — Engineering Enzyme Systems by Recombination (2014, Dissertation (Ph.D.))
• Sun, Lianhong — Engineering Galactose Oxidase to Increase Expression Level in E. coli, Enhance Thermostability and Introduce Novel Activities (2003, Dissertation (Ph.D.))
• Gao, Shilong — Engineering Heme Proteins for C(sp³)–H Primary Amination (2024, Dissertation (Ph.D.))
• Zhang, Ruijie — Engineering Heme Proteins for Olefin and Carbon−Hydrogen Bond Functionalization Reactions (2019, Dissertation (Ph.D.))
• Bedbrook, Claire Nicole — Engineering Novel Rhodopsins for Neuroscience (2018, Dissertation (Ph.D.))
• Brenner, Sarah Katherine — Engineering Synthetic Biofilm-Forming Microbial Consortia (2009, Dissertation (Ph.D.))
• Watkins-Dulaney, Ella Jenná — Engineering the Tryptophan Synthase β-Subunit for Synthesis of Noncanonical Amino Acids (2022, Dissertation (Ph.D.))
• Wu, Indira — Engineering Thermostable Fungal Cellobiohydrolases (2013, Dissertation (Ph.D.))
• Cahn, Jackson Kenai Blender — Engineering, Predicting, and Understanding Nicotinamide Cofactor Specificity (2016, Dissertation (Ph.D.))
• Zhao, Huimin — Enzyme Design by Directed Evolution (1998, Dissertation (Ph.D.))
• Li, Francesca-Zhoufan — Evaluation of the Generalizability of Machine Learning-Assisted Protein Engineering Methods (2025, Dissertation (Ph.D.))
• Lewis, Russell DeRieux — Evolution and Characterization of Carbene Transferases for Cyclopropanation and Carbon–Silicon Bond Formation (2019, Dissertation (Ph.D.))
• Lal, Ravi Goel — Expanding Enzyme Function Through Data-Guided Evolution (2026, Dissertation (Ph.D.))
• Truong, Frank — Expanding Protein Sequence Space through Incorporation of Non-Canonical Amino Acids (2013, Dissertation (Ph.D.))
• Chen, Kai — Expanding the Catalytic Repertoire of Hemeproteins as Carbene Transferases to Access Diverse Molecular Structures (2020, Dissertation (Ph.D.))
• Qin, Ziyang — Expanding the Chemical Space of Nitrene Transferases: Biocatalytic Construction of C–N Bonds (2026, Dissertation (Ph.D.))
• Knight, Anders Matthew — Expanding the Scope of Metalloprotein Families and Substrate Classes in New-to-Nature Reactions (2021, Dissertation (Ph.D.))
• Meyer, Michelle Margaret — Exploring Protein Sequence Space Using Computationally Directed Recombination (2006, Dissertation (Ph.D.))
• Flytzanis, Nicholas C. — From Single-Cell to Whole-Body: Developing a Molecular Neuroscience Toolkit (2019, Dissertation (Ph.D.))
• Bloom, Jesse D. — Hidden Dimensions in Protein Evolution: Stability, Mutational Robustness, and Evolvability (2007, Dissertation (Ph.D.))
• Claeys, Ivan Lode Andre Maria — Hydrodynamic Transport Properties of Suspensions of Non-Brownian Prolate Spheroids (1991, Dissertation (Ph.D.))
• Cirino, Patrick Carmen — Laboratory Evolution of Cytochrome P450 Peroxygenase Activity (2004, Dissertation (Ph.D.))
• Seressiotis, Alexandros — Mathematical Models Based on Molecular Processes of the Cell (1988, Dissertation (Ph.D.))
• Shanks, Jacqueline Vanni — Metabolic Engineering Applications of in vivo ³¹P and ¹³C NMR Studies of Saccharomyces cerevisiae (1989, Dissertation (Ph.D.))
• Hawkins, Kristy Michelle — Metabolic Engineering of Saccharomyces cerevisiae for the Production of Bensylisoquinoline Alkaloids (2009, Dissertation (Ph.D.))
• Guske, Christopher James — Metabolic modeling of growth and poly-[beta]-hydroxybutyrate (PHB) production in Alcaligenes eutrophus H16 (1990, Dissertation (Ph.D.))
• Lassila, Jonathan Kyle — Methods for Computational Enzyme Design and Application to the Chorismate-Prephenate Rearrangement (2007, Dissertation (Ph.D.))
• Chou, Hou-Pu — Microfabricated devices for rapid DNA diagnostics (2000, Dissertation (Ph.D.))
• Fu, Anne Yen-Chen — Microfabricated Fluorescence-Activated Cell Sorters (µFACS) for Screening Bacterial Cells (2002, Dissertation (Ph.D.))
• Maerkl, Sebastian Josef — Microfluidic Large Scale Integration and its Application to Systems Biology (2008, Dissertation (Ph.D.))
• Balagaddé, Frederick Kiguli — Microfluidic Technologies for Continuous Culture and Genetic Circuit Characterization (2007, Dissertation (Ph.D.))
• Thorsen, Todd Addison — Microfluidic Technologies for High-Throughput Screening Applications (2003, Dissertation (Ph.D.))
• Drummond, David Allan — Misfolding Dominates Protein Evolution (2006, Dissertation (Ph.D.))
• Johnson, Robert David — Multivalent Protein Binding to Metal-Complexing Materials: Applications to Synthetic Receptors and Affinity Chromatography (1995, Dissertation (Ph.D.))
• Wackelin, Daniel Joseph — New to Nature C–C Bond Forming Cyclases: Pushing the Boundaries of Ring Forming Reactions (2024, Dissertation (Ph.D.))
• Zhang, Juner — New-to-Nature Selective C-H Alkylation Using Engineered Carbene Transferases (2022, Dissertation (Ph.D.))
• Sun, Yun — NMR Studies of Protein-DNA Interactions: Determinations of DNA Structures Recognized by Bin Recombinase and Studies of Their Roles in Protein Binding Interactions (1992, Dissertation (Ph.D.))
• Lieblich, Seth Aharon — Non-Canonical Amino Acid Mutagenesis of Position B28 In Insulin with Proline Analogs (2017, Dissertation (Ph.D.))
• Smith, Matthew Alexander — Non-Contiguous Protein Recombination (2013, Dissertation (Ph.D.))
• Goldberg, Nathaniel Wood — Non-Native Chemistry of Metalloenzymes (2022, Dissertation (Ph.D.))
• Almhjell, Patrick James — Noncanonical Amino Acid Synthesis by Evolved Tryptophan Synthases (2023, Dissertation (Ph.D.))
• Coelho, Pedro de Souza Leão — Olefin Cyclopropanation and Carbon-Hydrogen Amination via Carbene and Nitrene Transfers Catalyzed by Engineered Cytochrome P450 Enzymes (2013, Dissertation (Ph.D.))
• Udit, Andrew K. — P450 BM3 Electrochemistry and Electrocatalysis (2005, Dissertation (Ph.D.))
• Wittrup, Karl Dane — Plasmid Propagation in the Yeast Saccharomyces cerevisiae: Flow Cytometry Studies and Segregated Modeling (1989, Dissertation (Ph.D.))
• Brown, David — Principles of Massively Parallel Sequencing for Engineering and Characterizing Gene Delivery (2022, Dissertation (Ph.D.))
• Yang, Kevin Kaichuang — Probabilistic Protein Engineering (2019, Dissertation (Ph.D.))
• Tang, Yi — Protein Engineering Using Unnatural Amino Acids: Incorporation of Leucine Analogs into Recombinant Protein in vivo (2002, Dissertation (Ph.D.))
• Kwon, Inchan — Protein Engineering via Site-Specific Incorporation of Nonnatural Amino Acids (2007, Dissertation (Ph.D.))
• Yoo, Tae Hyeon — Proteins of Novel Composition: Synthesis, Evolution, Dynamics (2008, Dissertation (Ph.D.))
• Bagert, John David — Quantitative, Time-Resolved Proteomic Analysis Using Bio-Orthogonal Non-Canonical Amino Acid Tagging (2015, Dissertation (Ph.D.))
• Komor, Russell Scott — Recombinatorial and Predictive Methods to Increase Cellulase Thermostability and Structural Analysis of a Thermostable P450 (2012, Dissertation (Ph.D.))
• Romero, Philip Anthony — Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering (2012, Dissertation (Ph.D.))
• Miao, Kun — Stimulated Raman Scattering: a Biophysical Perspective for Imaging Cells and Tissues (2024, Dissertation (Ph.D.))
• Wittmann, Bruce James — Strategies and Tools for Machine Learning-Assisted Protein Engineering (2022, Dissertation (Ph.D.))
• Otey, Christopher Richard — Structural and Functional Exploration of an Artificial Family of Cytochromes P450 (2008, Dissertation (Ph.D.))
• Przybycien, Todd Michael — Structure, Function and Aggregation Kinetics in Salt-Induced Protein Precipitation (1989, Dissertation (Ph.D.))
• Patrick, Valerie — Synthesis, Characterization, and Kinetics of Mixed Copper-Aluminum and Iron-Aluminum Oxides for High-Temperature Desulfurization (1989, Dissertation (Ph.D.))
• Mahdavi, Alborz — Synthetic Biology Tools for Targeted Incorporation of Non-Canonical Amino Acids into Cellular Proteins (2015, Dissertation (Ph.D.))
• Bayer, Travis Scott — Synthetic Regulation and Genetic Control of an Ecological Strategy (2009, Dissertation (Ph.D.))
• Tao, Yujia — Synthetic Studies Toward the Total Synthesis of Enterocin (2023, Dissertation (Ph.D.))
• Shnek, Deborah Rebecca — Targeting of Proteins and Protein Analogs to Metal-Chelating Lipid Vesicles (1996, Dissertation (Ph.D.))
• O'Connor, Kim Claire — The Effects of Immobilization on Structure and Substrate Activation of Glutamate Dehydrogenase (1987, Dissertation (Ph.D.))
• O'Meara, Ryen Logan — Towards the Enzymatic Mineralization of Siloxanes (2026, Dissertation (Ph.D.))
• Sheng, Gloria J. — Tunable Heparan Sulfate Glycomimetics for Modulating Chemokine Activity (2014, Dissertation (Ph.D.))
• Piraner, Dan Ilya — Tunable Thermal Bioswitches as a Control Modality for Next Generation Therapeutics (2019, Dissertation (Ph.D.))