Mayo, Stephen L.

Committee Member — 114 thesises

• Urbach, Adam Robert — 1:1 Motif for DNA Recognition by β-Alanine Linked Polyamides (2002, Dissertation (Ph.D.))
• Chen, Linlin — A Platform for High Throughput Discovery of Sequence Defined Affinity Reagents (2026, Dissertation (Ph.D.))
• Nisthal, Alex — Accelerating the Interplay Between Theory and Experiment in Protein Design (2012, Dissertation (Ph.D.))
• Johnston, Kadina Elizabeth — Acquiring Enzyme Sequence-Fitness Data at Scale Toward Predictive Methods for Enzyme Engineering (2024, Dissertation (Ph.D.))
• Hom, Geoffrey Kai Tong — Advances in Computational Protein Design: Development of More Efficient Search Algorithms and their Application to the Full-Sequence Design of Larger Proteins (2005, Dissertation (Ph.D.))
• Shah, Premal S. — Advances in Force Field Development and Sequence Optimization Methods for Computational Protein Design (2005, Dissertation (Ph.D.))
• Mai, Huanghao — Advancing Structural Analysis with Computational Methods Development (2025, Dissertation (Ph.D.))
• Zadeh, Joseph N. — Algorithms for Nucleic Acid Sequence Design (2010, Dissertation (Ph.D.))
• Nguyen Hackley, Doan Hanh — Allosteric Inhibition of Zinc Finger Proteins by DNA Binding Polyamides (2002, Dissertation (Ph.D.))
• Privett, Heidi Kathleen — An Iterative Approach to de novo Computational Enzyme Design and the Successful Application to the Kemp Elimination (2009, Dissertation (Ph.D.))
• Dirks, Robert Michael — Analysis, Design, and Construction of Nucleic Acid Devices (2005, Dissertation (Ph.D.))
• Mao, Jessica — Applications of Computational Protein Design (2006, Dissertation (Ph.D.))
• Moore, Matthew Michaels — Applications of Computational Protein Design to Red Fluorescent Proteins (2013, Dissertation (Ph.D.))
• Link, Aaron James — Azide-Bearing Amino Acids in Protein Engineering and Proteomic Profiling (2006, Dissertation (Ph.D.))
• Su, Yao-ying Alyce — Backbone Flexibility in Protein Design Theory and Experiment (1998, Dissertation (Ph.D.))
• Walkup, Ward Gale IV — Biochemical Studies of Postsynaptic Density Signaling Proteins With a Focus on synGAP and PDZ Domains (2014, Dissertation (Ph.D.))
• Szablowski, Jerzy Olgierd — Biological Activity of Pyrrole-Imidazole Polyamides in vivo (2015, Dissertation (Ph.D.))
• Lovely, Geoffrey A. — Biophysics of V(D)J Recombination and Genome Packaging: In Singulo Studies on RAG, HMGB1, and TFAM (2014, Dissertation (Ph.D.))
• Lourenço, Alexandre Luiz — Building Closed-Loop Frameworks for AI-Guided Protein Design (2025, Dissertation (Ph.D.))
• Wang, Jingzhou — CDRxAb: Antibody Small-Molecule Conjugates with Computationally Designed Target-Binding Synergy (2021, Dissertation (Ph.D.))
• Strop, Pavel — Characterization of the Mechanosensitive Channel of Large Conductance (2002, Dissertation (Ph.D.))
• Gordon, David Benjamin — Combinatorial Optimization in Computational Protein Design (2000, Dissertation (Ph.D.))
• Hsu, Carey Frank — Completion of a Programmable DNA-Binding Small Molecule Library (2009, Dissertation (Ph.D.))
• Huang, Po-Ssu — Computational Design and Experimental Characterization of Protein Oligomers (2004, Dissertation (Ph.D.))
• Friesenhahn, Nicholas James — Computational Design of Protein-Based Biosensors for Nicotine (2026, Dissertation (Ph.D.))
• Mou, Yun — Computational Design of Self-Assembling Proteins and Protein-DNA Nanowires (2014, Dissertation (Ph.D.))
• Bolon, Daniel N. — Computational Enzyme Design (2002, Dissertation (Ph.D.))
• Sosa Padilla Araujo, Bernardo — Computational Enzyme Design (2014, Dissertation (Ph.D.))
• Gonzalvo i Ulla, Marta — Computational Methods for Nucleic Acid Structure Prediction and G Protein-Coupled Receptor Mechanism Investigation (2025, Dissertation (Ph.D.))
• Kirkpatrick, Andrea — Computational Predictions of G Protein-Coupled Receptor Structures and Binding Sites (2015, Dissertation (Ph.D.))
• Alvizo, Oscar — Computational Protein Design Force Field Optimization: A Negative Design Approach (2007, Dissertation (Ph.D.))
• Wannier, Timothy Milton — Computationally Guided Monomerization of Red Fluorescent Proteins of the Class Anthozoa (2015, Dissertation (Ph.D.))
• Voigt, Christopher Ashby — Computationally Optimizing the Directed Evolution of Proteins (2003, Dissertation (Ph.D.))
• Lee, Toni Marie — Computationally-Guided Thermostabilization of the Primary Endoglucanase from Hypocrea jerorina for Cellulosic Biofuel Production (2014, Dissertation (Ph.D.))
• Zhang, Raymond J. — Construction of Bacterial Genome Chimeras (2026, Dissertation (Ph.D.))
• Hamburger, Zsuzsa Andrea — Crystallographic Studies of Invasin, a Bacterial Adhesion Molecule from Yersinia pseudotuberculosis (2002, Dissertation (Ph.D.))
• Endelman, Jeffrey B. — Design and Analysis of Combinatorial Protein Libraries Created by Site-Directed Recombination (2005, Dissertation (Ph.D.))
• Stafford, Ryan Leonard — Design of Protein-DNA Dimerizers (2008, Dissertation (Ph.D.))
• Berry, Alexandria Helen T. — Designing Conformational Control of Human Tissue Transglutaminase (2014, Dissertation (Ph.D.))
• Choi, Eun Jung — Development and Applications of Computational Protein Design (2006, Dissertation (Ph.D.))
• Vizcarra, Christina Luisa — Development and Evaluation of Protein Design Methods for Functional Targets (2008, Dissertation (Ph.D.))
• Allen, Benjamin Daniel — Development and Validation of Optimization Methods for the Design of Protein Sequences and Combinatorial Libraries (2009, Dissertation (Ph.D.))
• Huang, Shan — DNA-Guided Genome Manipulation in Escherichia coli (2023, Dissertation (Ph.D.))
• Poulin-Kerstien, Adam Thomas — DNA-Templated Dimerizations of Minor Groove-Binding Polyamides (2005, Dissertation (Ph.D.))
• Bugg, Charles Walter — Domain Organization of Mutant Huntingtin Fibrils (2011, Dissertation (Ph.D.))
• Ceres, Donato Marino — Electron Transfer at DNA-Modified Electrodes (2006, Dissertation (Ph.D.))
• Nickols, Nicholas George — Endogenous Gene Regulation by DNA Binding Polyamides (2008, Dissertation (Ph.D.))
• Hamdouche, Samy — Engineered Antibody and Monobody Domains with T Cell Receptor-Like Selectivity for Tumor Associated Peptide-MHC Antigens (2014, Dissertation (Ph.D.))
• Kym, Eugene Yongshik (Gene) — Engineered Discoidin Domain from Factor VIII Binds αvβ3 Integrin with Antibody-like Affinity (2014, Dissertation (Ph.D.))
• Keeffe, Jennifer Rae — Engineering Cyanovirin-N for Enhanced Viral Neutralization (2009, Dissertation (Ph.D.))
• Trudeau, Devin Lee — Engineering Enzyme Systems by Recombination (2014, Dissertation (Ph.D.))
• Caldera, Luis Fernando — Engineering Immunological Solutions for Pandemic-Level Threats (2026, Dissertation (Ph.D.))
• Petersen, Philip Fai — Engineering Molecular Self-assembly and Reconfiguration in DNA Nanostructures (2018, Dissertation (Ph.D.))
• Wu, Indira — Engineering Thermostable Fungal Cellobiohydrolases (2013, Dissertation (Ph.D.))
• Cahn, Jackson Kenai Blender — Engineering, Predicting, and Understanding Nicotinamide Cofactor Specificity (2016, Dissertation (Ph.D.))
• Li, Francesca-Zhoufan — Evaluation of the Generalizability of Machine Learning-Assisted Protein Engineering Methods (2025, Dissertation (Ph.D.))
• Lal, Ravi Goel — Expanding Enzyme Function Through Data-Guided Evolution (2026, Dissertation (Ph.D.))
• Truong, Frank — Expanding Protein Sequence Space through Incorporation of Non-Canonical Amino Acids (2013, Dissertation (Ph.D.))
• Wang, Pin — Expanding the Biosynthetic Capacity of the Aminoacyl-tRNA Synthetases (2004, Dissertation (Ph.D.))
• Cornejo de los Santos, Emmanuel Lorenzo — Expanding the Toolkit for Synthetic Biology: Frameworks for Native-like Non-natural Gene Circuits (2015, Dissertation (Ph.D.))
• Sarisky, Catherine Ann — Exploration of the Determinants of Protein Structure and Stability by Protein Design (2005, Dissertation (Ph.D.))
• Meyer, Michelle Margaret — Exploring Protein Sequence Space Using Computationally Directed Recombination (2006, Dissertation (Ph.D.))
• Miskevich, Frank — Expression, Characterization, and Ligand Studies Involving Domains of the Chick Cell Surface Protein Neogenin (1997, Dissertation (Ph.D.))
• Zollars, Eric Stafford — Force Field Development in Protein Design (2006, Dissertation (Ph.D.))
• Morgan, Chantal Smith — Full Sequence Design of an Alpha-Helical Protein and Investigation of the Importance of Helix Dipole and Capping Effects in Helical Protein Design (2000, Dissertation (Ph.D.))
• Bloom, Jesse D. — Hidden Dimensions in Protein Evolution: Stability, Mutational Robustness, and Evolvability (2007, Dissertation (Ph.D.))
• Marshall, Stephen Sandell — Improvement of Integral Membrane Protein Expression via Optimization of Simulated Integration Efficiency (2018, Dissertation (Ph.D.))
• Li, Shuwei — In Vitro Selection of mRNA-Display Libraries Containing Unnatural Amino Acids (2003, Dissertation (Ph.D.))
• Takahashi, Terry Torao — In Vitro Selection of RNA Binding Peptides (2005, Dissertation (Ph.D.))
• Breunig, Stephanie Lynne — Incorporation of Non-Canonical Proline Residues into Proteins Expressed in Escherichia coli (2023, Dissertation (Ph.D.))
• Nguyen, Tyler Minh-Hung — Infrared Action Spectroscopy of Biomolecules for Planetary Science Applications (2026, Dissertation (Ph.D.))
• Bremer, Ryan Elwood — Inhibition of DNA Major Groove Binding Proteins by Hairpin Polyamides (2000, Dissertation (Ph.D.))
• Klein, Joshua Simon — Investigations in the Design and Characterization of HIV-1 Neutralizing Molecules (2009, Dissertation (Ph.D.))
• Zeglis, Brian Matthew — Investigations into the Generality of Metalloinsertion at DNA Defects (2010, Dissertation (Ph.D.))
• Aceves, Aiden Joseph — Machine Learning and Modeling Methods for Protein Engineering (2022, Dissertation (Ph.D.))
• Lee, Jennifer Chen — Mapping Heme Protein Folding Landscapes (2002, Dissertation (Ph.D.))
• Mahajan, Shivansh — Mechanistic Studies of ArsA ATPase and ArsB Transporter of the Bacterial Arsenite Efflux System (2026, Dissertation (Ph.D.))
• Hawkins, Kristy Michelle — Metabolic Engineering of Saccharomyces cerevisiae for the Production of Bensylisoquinoline Alkaloids (2009, Dissertation (Ph.D.))
• Lassila, Jonathan Kyle — Methods for Computational Enzyme Design and Application to the Chorismate-Prephenate Rearrangement (2007, Dissertation (Ph.D.))
• Puckett, James William — Microarray and Genome-wide Sequencing Approaches to Characterizing DNA Binding Molecules (2009, Dissertation (Ph.D.))
• Anderson, Megan Jo — Microfluidics-Based Strategies for Protein Crystallography (2009, Dissertation (Ph.D.))
• Fang, Katharine Yan — Modulating Biophysical Properties of Insulin with Non-Canonical Mutagenesis at Position B28 (2017, Dissertation (Ph.D.))
• Vaughn, Daniel E. — Molecular Mechanism of pH Dependent Antibody Binding: Structure/Function Studies on the Neonatal Fc Receptor (1998, Dissertation (Ph.D.))
• Liu, Yang — Molecular Mechanism of Sulfated Carbohydrate Recognition: Structural and Biochemical Studies of the Cysteine-Rich Domain of Mannose Receptor (2001, Dissertation (Ph.D.))
• Muthusamy, Anand Kumar — Neuropsychiatric Drug Biosensors in Organelles, Cells, Biofluids, & Behaving Animals (2024, Dissertation (Ph.D.))
• Pascal, Tod Augustin — New Approaches to Accurate Predictions of Free Energies: From Proteins to Organic Nanostructures (2010, Dissertation (Ph.D.))
• Lieblich, Seth Aharon — Non-Canonical Amino Acid Mutagenesis of Position B28 In Insulin with Proline Analogs (2017, Dissertation (Ph.D.))
• Almhjell, Patrick James — Noncanonical Amino Acid Synthesis by Evolved Tryptophan Synthases (2023, Dissertation (Ph.D.))
• Lancaster, Kyle Matthew — Outer-Sphere Effects on the Copper Sites of Pseudomonas Aeruginosa Azurins (2011, Dissertation (Ph.D.))
• Dahiyat, Bassil I. — Protein Design Automation : Principles and Practice (1998, Dissertation (Ph.D.))
• Chitsaz, Mohsen — Protein Structure Refinement Algorithms (2014, Dissertation (Ph.D.))
• Datta, Deepshikha — Protein-Ligand Interactions: Docking, Design and Conformation Change (2003, Dissertation (Ph.D.))
• Komor, Russell Scott — Recombinatorial and Predictive Methods to Increase Cellulase Thermostability and Structural Analysis of a Thermostable P450 (2012, Dissertation (Ph.D.))
• Subramanian, Arjuna Michael — Rewriting the Sequence and Structure Rules of Deep Protein Space (2026, Dissertation (Ph.D.))
• Wurtz, Nicholas Roland — Sequence Specific Alkylation of DNA by Polyamide-Chlorambucil Conjugates (2002, Dissertation (Ph.D.))
• Luong, Tinh Nghi — Signaling Proteins in the Post-Synaptic Density (2010, Dissertation (Ph.D.))
• Marcus, Joshua Scott — Single Mammalian Cell Gene Expression Analysis Using Microfluidics (2006, Dissertation (Ph.D.))
• Austin, Ryan James — Solving Molecular Recognition Problems with Evolvable Peptide Motifs (2007, Dissertation (Ph.D.))
• Marshall, Shannon Alicia — Stability and Conformational Specificity in Protein Design: Models for Binary Patterning and Electrostatics (2002, Dissertation (Ph.D.))
• Luo, Ji-Ye — Stability and Dynamics Studies of Apo-Azurin from Pseudomonas aeruginosa (1997, Dissertation (Ph.D.))
• Romero, Philip Anthony — Statistical Models of the Protein Fitness Landscape: Applications to Protein Evolution and Engineering (2012, Dissertation (Ph.D.))
• Herman, David Matthew — Stereochemically Modified Polyamides for Recognition in the Minor Groove of DNA (2001, Dissertation (Ph.D.))
• Wittmann, Bruce James — Strategies and Tools for Machine Learning-Assisted Protein Engineering (2022, Dissertation (Ph.D.))
• Bhattacharya, Pratip K. — Structure and Reactivity of Metal Complexes Bound to DNA (2004, Dissertation (Ph.D.))
• Gillespie, Sarah Knox — Structure-Guided SCHEMA Recombination of VRC01-Class Antibodies for Reduced Polyreactivity (2025, Dissertation (Ph.D.))
• Schaus, Lucas Jean Nicolas — Studies on Scaling Throughput in Protein Engineering (2025, Dissertation (Ph.D.))
• Hart, Jonathan Ross — Synthesis and Applications of Bulky Rhodium(III) Intercalators for the Recognition of DNA Mismatches (2006, Dissertation (Ph.D.))
• Olson, Blade A. — Synthetic Antigen-Presenting Vesicles for Selective Immunomodulation (2026, Dissertation (Ph.D.))
• Poon, Yan Shuen — The Characterization and Structure of Mechanosensitive Channels of Small Conductance (2008, Dissertation (Ph.D.))
• Marques, Michael Anthony — The Molecular Recognition of DNA by Novel Heterocycles (2005, Dissertation (Ph.D.))
• Street, Arthur George — Understanding and Designing Protein Beta-Sheets (2000, Dissertation (Ph.D.))
• Wang, Connie Yuan-Ying — Understanding Co-Translational Protein Targeting and Lithium Dendrite Formation through Free Energy Simulations and Coarse-Grained Models (2016, Dissertation (Ph.D.))
• Yu, Changhua — Understanding Kinase-Substrate Interaction with Deep Learning and High-Throughput Scanning (2026, Dissertation (Ph.D.))
• Qi, Xin — Unnatural Amino Acid Incorporation to Rewrite the Genetic Code and RNA-Peptide Interactions (2005, Dissertation (Ph.D.))